반응 #955955

반응 방정식

acetic anhydride

butyl pyruvate

acetic anhydride

→

butyl α-acetoxyacrylate

수율 67.1%

용매

acetic acid

반응 조건

후처리

1. 1
   workup.ADDITIONwas added
2. 2
   기타to obtain a second reaction solution
3. 3
   기타was removed from the second reaction solution
4. 4
   workup.DISTILLATIONThereafter, the residue was purified by reduced pressure distillation (2 mmHg, 56 to 63° C.)

실험 절차

Next, in a mixture of the obtained butyl pyruvate (235 g, 1.6 mol) and acetic anhydride (333 g, 3.3 mol), p-toluenesulfonic acid monohydrate (5 g) was added. Then, the mixture was stirred under a nitrogen gas stream at 120° C. for 25 hours to obtain a second reaction solution. Next, acetic acid generated by a reaction with excess acetic anhydride under reduced pressure (5 mmHg) was removed from the second reaction solution. Thereafter, the residue was purified by reduced pressure distillation (2 mmHg, 56 to 63° C.) to obtain butyl α-acetoxyacrylate (200 g, yield 67%).

출처