반응 #955742

반응 방정식

isatin

3-diisopropylaminopropyl chloride hydrochloride

→

1-(3-diisopropylaminopropyl)isatin

수율 72.9%

반응 조건

후처리

1. 1
   기타the reaction product was purified with silica gel column chromatography (eluent: chloroform/methanol=50/1)
2. 2
   기타recrystallized from hexane

실험 절차

By using isatin and 3-diisopropylaminopropyl chloride hydrochloride, a method analogous to that described in Reference Example 1 was carried out, and the reaction product was purified with silica gel column chromatography (eluent: chloroform/methanol=50/1) and then recrystallized from hexane to obtain 1-(3-diisopropylaminopropyl)isatin having a melting point of 49°-50° C. (yield: 72.9%).

출처