반응 #95491

반응 방정식

1-phenylspiro[indoline-3,4'-piperidine]

propionyl chloride

sodium bicarbonate

→

1-phenyl-1'-propionylspiro[indoline-3,4'-piperidine]

용매

chloroform

반응 조건

후처리

1. 1
   온도at reflux
2. 2
   온도to cool
3. 3
   여과filtered
4. 4
   농축the filtrate concentrated

실험 절차

A mixture of 1-phenylspiro[indoline-3,4'-piperidine] (Example 11), propionyl chloride and sodium bicarbonate in chloroform is stirred at reflux. The mixture is permitted to cool, filtered, and the filtrate concentrated, leaving 1-phenyl-1'-propionylspiro[indoline-3,4'-piperidine]. In a similar fashion, 1-phenylspiro[indoline-3,4'-piperidine] is treated with benzoylchloride to provide 1'-benzoyl-1-phenylspiro[indoline-3,4'-piperidine].

출처