반응 #95468

반응 방정식

(Z)-8-tetradecen-2-yn-1-ol

phosphorous tribromide

→

(Z)-1-bromo-8-tetradecen-2-yne

용매

ether

반응 조건

후처리

1. 1
   온도under reflux for 2.0 h
2. 2
   기타to give 3.83 g of crude product
3. 3
   workup.DISTILLATIONIt was purified by evaporative distillation at 105° C.-120° C./0.25 mm

실험 절차

By the procedure of example 14, 3.82 g (18.34 mmol) of (Z)-8-tetradecen-2-yn-1-ol, 72 mg of dry pyridine, and 1.66 g (6.12 mmol) of phosphorous tribromide were reacted in 20 ml of ether under reflux for 2.0 h. It was worked up as described in example 14 to give 3.83 g of crude product. It was purified by evaporative distillation at 105° C.-120° C./0.25 mm to yield 3.64 g (73% by weight yield) of (Z)-1-bromo-8-tetradecen-2-yne as a colorless oil.

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