반응 #95434

반응 방정식

hydantoin

4-nitrobenzaldehyde

ammonium acetate

acetic acid

→

5-(4'-nitrobenzylidene)-hydantoin

수율 93.9%

용매

n-butanol

반응 조건

후처리

1. 1
   온도at reflux temperature

실험 절차

A mixture of 100 grams (1.0 mole) of hydantoin, 151 grams (1.0 mole) of 4-nitrobenzaldehyde, 77 grams (1.0 mole) of ammonium acetate, 120 grams (2.0 moles) of acetic acid, and 200 ml of n-butanol were held for 3 hours at reflux temperature. After the cooling, there were obtained 219 grams of 5-(4'-nitrobenzylidene)-hydantoin, corresponding to 94% of the theory based on hydantoin. The product had a melting point of 253°-254° C. and homogeneous by thin layer chromatography.

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