반응 #95102

반응 방정식

5-hydroxy-3-phenyl-1H-2-indole carboxylic acid ethylester

potassium carbonate

benzylbromide

→

5-Benzyloxy-3-phenyl-1H-2indole carboxylic acid ethylester

용매

methyl-ethylketone

반응 조건

후처리

1. 1
   여과After filtration and evaporation
2. 2
   기타the residue was chromatographed on silicagel (solvent: toluene)

실험 절차

Twenty-six grams (92.4 m mole) of 5-hydroxy-3-phenyl-1H-2-indole carboxylic acid ethylester were refluxed for four days with 27.6 g of potassium carbonate and 11 ml (92.4 mole) of benzylbromide in 700 ml of methyl-ethylketone. After filtration and evaporation, the residue was chromatographed on silicagel (solvent: toluene).

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