반응 #95097

ord-d3f3438c083c4fb2b65db288b05789a2

반응 방정식

CCCCCCCCCC(C)NC(=O)[C@@H]1C[C@H]1c1ccc([N+](=O)[O-])cc1
trans-N-(1-methyldecyl)-2-(4-nitrophenyl)cyclopropanecarboxamide
→
CCCCCCCCCC(C)NC(=O)[C@@H]1C[C@H]1c1ccc(N)cc1
title compound
CCCCCCCCCC(C)NC(=O)[C@@H]1C[C@H]1c1ccc(N)cc1
trans-N-(1-Methyldecyl)-2-(4-aminophenyl)cyclopropanecarboxamide

반응물

CCCCCCCCCC(C)NC(=O)[C@@H]1C[C@H]1c1ccc([N+](=O)[O-])cc1
trans-N-(1-methyldecyl)-2-(4-nitrophenyl)cyclopropanecarboxamide

시약

[Fe]
iron

용매

CC(=O)O
acetic acid

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타in a manner analogous to Preparation 34

실험 절차

The title compound was prepared in essentially quantitative yield by reducing trans-N-(1-methyldecyl)-2-(4-nitrophenyl)cyclopropanecarboxamide with iron powder in glacial acetic acid, in a manner analogous to Preparation 34.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04343813uspto-grants-1982_08