반응 #95047

반응 방정식

chloroacetonitrile

3-cyanophenol

potassium carbonate

dimethylformamide

→

3-cyanophenoxyacetonitrile

용매

water

반응 조건

후처리

1. 1
   기타The compound 3-cyanophenoxyacetonitrile was prepared
2. 2
   온도with cooling
3. 3
   기타resulted in crystal formation
4. 4
   기타The crystals were separated
5. 5
   여과by filtering
6. 6
   세척washed thoroughly with water
7. 7
   기타After drying in a vacuum oven

실험 절차

The compound 3-cyanophenoxyacetonitrile was prepared by heating 20.0 g of 3-cyanophenol, 30.1 g of anhydrous potassium carbonate and 30 ml of dimethylformamide with stirring in a 250 ml round-bottomed three-necked flask to 70° C. and then 12.7 g of chloroacetonitrile was added dropwise over a 15 minute period with cooling. The temperature of the mixture was held at 70°-80° C. for three hours, after which time the reaction mixture was poured into approximately 700 ml of ice and water which resulted in crystal formation. The crystals were separated by filtering and then washed thoroughly with water. After drying in a vacuum oven, a tan solid 3-cyanophenoxyacetonitrile was obtained.

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