반응 #95011

반응 방정식

2,3-dichloropyrazine

sodium

methanol

→

2-chloro-3-methoxypyrazine

용매

water

반응 조건

후처리

1. 1
   추출The product is extracted with ether or chloroform
2. 2
   기타recrystallized from a suitable solvent such as ethanol

실험 절차

A mixture of 0.1 mole of 2,3-dichloropyrazine and 2.3 g. (0.1 mole) of sodium in 160 ml. of anhydrous methanol is refluxed 5-10 hours, and poured into water. The product is extracted with ether or chloroform and recrystallized from a suitable solvent such as ethanol to give pure 2-chloro-3-methoxypyrazine.

출처