반응 #9460

반응 방정식

(3-Methylsulfanylpropyl)-(3-nitro-7-phenylquinolin-4-yl)amine

→

N4-(3-methylsulfanylpropyl)-7-phenylquinoline-3,4-diamine

수율 100.0%

용매

toluene

반응 조건

후처리

1. 1
   여과The reaction mixture was filtered through CELITE
2. 2
   여과filter agent
3. 3
   세척washed with methanol (100 mL) and CHCl3 (50 mL)
4. 4
   농축concentrated

실험 절차

(3-Methylsulfanylpropyl)-(3-nitro-7-phenylquinolin-4-yl)amine (3.0 g, 8.5 mmol) was hydrogenated in a Parr bottle over Pt/C (0.3 g of 5%) in 42 mL of toluene for 1 h. The reaction mixture was filtered through CELITE filter agent, washed with methanol (100 mL) and CHCl3 (50 mL), and then concentrated to afford 2.75 g of N4-(3-methylsulfanylpropyl)-7-phenylquinoline-3,4-diamine as a brown oil.

출처