반응 #94528

반응 방정식

sodium hydroxide

2,6-diethyl-2,3,6-trimethylpiperidine

allyl bromide

→

1-allyl-2,6-diethyl-2,3,6-trimethylpiperidine

용매

2

2,4,6-tripropyl-2,6-dimethyl-1,2,5,6-tetrahydropyrimidine

반응 조건

후처리

1. 1
   추출is extracted with ether
2. 2
   건조The ethereal solution is dried over K2CO3
3. 3
   기타evaporated
4. 4
   workup.DISTILLATIONThe residue is purified by fractional distillation

실험 절차

36.7 g of 2,6-diethyl-2,3,6-trimethylpiperidine and 30 g of allyl bromide are stirred for 7 days with heating at about 75° C. The reaction mixture is made alkaline by addition of 200 ml of 2 n sodium hydroxide and is extracted with ether. The ethereal solution is dried over K2CO3 and evaporated. The residue is purified by fractional distillation yielding 1-allyl-2,6-diethyl-2,3,6-trimethylpiperidine (Compound No. 4) which distills at 132°-135° C./16 mm Hg.

출처