반응 #94476

반응 방정식

4-Nitrostyrylsulfonyl chloride

4-nitrobenzamidine

triethylamine

→

N-(4-NITROSTYRYLSULFONYL)-4-NITROBENZAMIDINE

용매

acetone

반응 조건

후처리

1. 1
   기타prepared
2. 2
   기타at 10° C
3. 3
   농축at 25° C., the mixture is concentrated under reduced pressure
4. 4
   workup.STIRRINGthe residual material stirred with water
5. 5
   기타collected
6. 6
   기타Triturating the filter cake with acetone

실험 절차

4-Nitrostyrylsulfonyl chloride (2.5 g., 0.01 mole) is added portion-wise to a solution of 4-nitrobenzamidine (1.65 g., 0.01 mole), prepared according to the procedure of L. Weintraub, et al., J. Org. Chem., 33, 1679 (1968), and triethylamine (1.01 g., 0.01 mole) in 50 ml. of acetone at 10° C. After stirring for a period of 1 hr. at 25° C., the mixture is concentrated under reduced pressure and the residual material stirred with water and collected. Triturating the filter cake with acetone provides N-(4-NITROSTYRYLSULFONYL)-4-NITROBENZAMIDINE, m.p. 173°-177° C.

출처