반응 #94311

반응 방정식

4-amino-5-hydroxy-1,7-naphthalenedisulfonic acid

sodium acetate trihydrate

2-methyl-5-nitrobenzoyl chloride

→

5-hydroxy-4-(5-nitro-o-toluamido)-1,7-naphthalenedisulfonic acid

용매

water

반응 조건

후처리

1. 1
   여과The solid is then collected by filtration
2. 2
   세척washed with water, 80% ethanol, ethanol, ether
3. 3
   기타dried

실험 절차

A 16 g portion of 4-amino-5-hydroxy-1,7-naphthalenedisulfonic acid in 120 ml of water is adjusted to pH7.2. A 7.6 g portion of sodium acetate trihydrate and 8.8 g of 2-methyl-5-nitrobenzoyl chloride are added with vigorous stirring. The mixture is stirred overnight at room temperature. The solid is then collected by filtration, washed with water, 80% ethanol, ethanol, ether and dried, giving 13.0 g of 5-hydroxy-4-(5-nitro-o-toluamido)-1,7-naphthalenedisulfonic acid, disodium salt.

출처