반응 #94215

반응 방정식

6-benzylsulfamoyl-5-chloro-1-indanone

bromine

→

6-Benzylsulfamoyl-2-bromo-5-chloro-1-indanone

용매

acetic acid

반응 조건

후처리

1. 1
   기타yield the substance
2. 2
   기타of from 159° to 161° C. which
3. 3
   기타after reprecipitation
4. 4
   workup.ADDITIONfrom a mixture of ethyl acetate and petroleum ether
5. 5
   기타of from 176° to 178° C.

실험 절차

According to Example 1 e), 10.05 g (30 mmoles) of 6-benzylsulfamoyl-5-chloro-1-indanone and 4.8 g (30 mmoles) of bromine in a total of 110 ml of glacial acetic acid yield the substance having a melting point of from 159° to 161° C. which after reprecipitation from a mixture of ethyl acetate and petroleum ether has a melting point in the range of from 176° to 178° C.

출처