반응 #94210

반응 방정식

5-chloro-6-chlorosulfonyl-1-indanone

ammonia

→

5-Chloro-6-sulfamoyl-1-indanone

용매

반응 조건

후처리

1. 1
   기타to evaporate
2. 2
   workup.DISSOLUTIONthe residue is dissolved in water
3. 3
   온도is heated within a short time on the water-bath
4. 4
   여과is filtered
5. 5
   workup.ADDITIONafter the addition of active charcoal
6. 6
   여과the precipitate is filtered off with suction
7. 7
   세척is washed with water
8. 8
   기타is in the range of from 205° to 208° C.
9. 9
   기타after recrystallization
10. 10
    workup.ADDITIONfrom a mixture of acetone and water it
11. 11
    기타is 216° to 218° C.

실험 절차

99.6 Grams of 5-chloro-6-chlorosulfonyl-1-indanone are introduced portionwise into 700 ml of liquid ammonia. The solvent is allowed to evaporate and the residue is dissolved in water, is heated within a short time on the water-bath and is filtered after the addition of active charcoal. The solution is acidified with hydrochloric acid to a pH of 2, the precipitate is filtered off with suction and is washed with water. The melting point of 5-chloro-6-sulfamoyl-1-indanone is in the range of from 205° to 208° C., and after recrystallization from a mixture of acetone and water it is 216° to 218° C.

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