반응 #94085

반응 방정식

1-methoxybutan-3-one

diethyl ketone

sodium methylate

acetic acid

→

2,3,6-trimethyl-2-cyclohexen-1-one

4-methyl-3-ethyl-2-cyclohexen-1-one

용매

methanol

반응 조건

후처리

1. 1
   온도The whole is then heated
2. 2
   온도under reflux for another hour

실험 절차

152 g of 1-methoxybutan-3-one is dripped in the course of one hour into a boiling mixture of 400 g of diethyl ketone and 5 g of a 30% by weight solution of sodium methylate in methanol. The whole is then heated under reflux for another hour. The reaction mixture is neutralized with glacial acetic acid and then fractionated. 70 g of 2,3,6-trimethyl-2-cyclohexen-1-one and 9 g of 4-methyl-3-ethyl-2-cyclohexen-1-one is obtained. The total yield of cyclohexenone is 57% with reference to 1-methoxybutan-3-one.

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