반응 #94081

반응 방정식

diethyl ketone

β-methoxybutyraldehyde

sodium methylate

→

2,5,6-trimethyl-2-cyclohexen-1-one

수율 56.0%

용매

methanol

반응 조건

후처리

1. 1
   온도under reflux
2. 2
   온도The whole is then heated for another hour
3. 3
   온도under reflux

실험 절차

102 g of β-methoxybutyraldehyde is dripped in the course of one hour into a mixture of 500 g of diethyl ketone and 10 g of a 30% solution of sodium methylate in methanol which is boiling under reflux. The whole is then heated for another hour under reflux. The reaction mixture is processed as described in Example 2. 77 g of 2,5,6-trimethyl-2-cyclohexen-1-one is obtained, i.e. a 56% yield with reference to β-methoxybutyraldehyde.

출처