반응 #94031

반응 방정식

2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethanamine

S-methyl-N-nitroisothiourea

→

N-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl]-N'-nitroguanidine

용매

ethanol

반응 조건

후처리

1. 1
   여과The resulting precipitate was filtered
2. 2
   기타recrystallised from ethyl acetate and petroleum ether b.p. 80°-100°

실험 절차

A solution of 2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethanamine (2.14 g) and S-methyl-N-nitroisothiourea (1.5 g) in ethanol (10 ml) was heated to 40° for 5 mins. The resulting precipitate was filtered and recrystallised from ethyl acetate and petroleum ether b.p. 80°-100° to give N-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl]-N'-nitroguanidine m.p. 103°-104°.

출처