반응 #94029

반응 방정식

2-[[[5-(Dimethylamino)methyl-2-furanyl]methyl]thio]ethanamine

isopropylisocyanate

→

2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl-N'-(1-methylethyl)urea

수율 93.7%

용매

acetonitrile

반응 조건

후처리

1. 1
   기타Solvents were removed
2. 2
   기타the residue recrystallised from methanol

실험 절차

2-[[[5-(Dimethylamino)methyl-2-furanyl]methyl]thio]ethanamine (2.14 g) and isopropylisocyanate (0.89 g) were dissolved in acetonitrile and allowed to stand overnight. Solvents were removed and the residue recrystallised from methanol:ether to give N-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl-N'-(1-methylethyl)urea as crystals m.p. 65°-67° (2.8 g).

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