반응 #939027

ord-6f8ac4ad6ece44e596a4f65f55eb6963

반응 방정식

COCCOCCCl
2-chloroethyl 2-methoxyethyl ether
CCc1nc2ccccc2[nH]1
2-ethylbenzimidazole
CCc1nc2ccccc2n1CCOCCOC
2-Ethyl-1-[2-(2-methoxyethoxy)ethyl]-1H-benzimidazole
수율 77.0%

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

2-Ethyl-1-[2-(2-methoxyethoxy)ethyl]-1H-benzimidazole was synthesized as in Synthesis Example 1 except that an equimolar amount of 2-ethylbenzimidazole was used instead of benzimidazole and an equimolar amount of 2-chloroethyl 2-methoxyethyl ether was used instead of 2-chloroethyl methyl ether. Yield 77%.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07252925B2uspto-grants-2007_08