반응 #939026

ord-039741a18ff34bcf95544b62301747df

반응 방정식

COCCOCCCl
2-chloroethyl 2-methoxyethyl ether
Cc1nc2ccccc2[nH]1
2-methylbenzimidazole
COCCOCCn1c(C)nc2ccccc21
1-[2-(2-Methoxyethoxy)ethyl]-2-methyl-1H-benzimidazole
수율 78.0%

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

1-[2-(2-Methoxyethoxy)ethyl]-2-methyl-1H-benzimidazole was synthesized as in Synthesis Example 1 except that an equimolar amount of 2-methylbenzimidazole was used instead of benzimidazole and an equimolar amount of 2-chloroethyl 2-methoxyethyl ether was used instead of 2-chloroethyl methyl ether. Yield 78%.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07252925B2uspto-grants-2007_08