반응 #939021

ord-7e233837b41f4ef9a3784255f4e715dd

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    온도was refluxed for 2 days
  2. 2
    기타water removed from the reaction mixture
  3. 3
    기타After reaction
  4. 4
    기타solvent was removed in vacuuo
  5. 5
    기타to yield a viscous oil

실험 절차

A mixture of 1,2,3-propanetricarboxylic acid (25 g), cyclohexanol (55 g), and p-toluenesulfonic acid (100 mg) in toluene (500 mL) was refluxed for 2 days and water removed from the reaction mixture. After reaction was complete, solvent was removed in vacuuo to yield a viscous oil. The crude material was redissolved in heptane and passed through a pad of silica gel to obtain 1,2,3-propanetricarboxylic acid tricyclohexyl ester (50 g) as a pale yellow oil.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07252865B2uspto-grants-2007_08