반응 #939019

반응 방정식

6-decenoic acid

Methyl 6-bromodecanoate

quinoline

methyl 5-decenoate

methyl 6-decenoate

→

5-decenoic acid

수율 35.0%

반응 조건

후처리

1. 1
   기타to react at 240° C. for 5 minutes
2. 2
   추출the reaction solution was extracted with ether
3. 3
   세척washed with dilute sulfuric acid
4. 4
   세척washed with water
5. 5
   기타dried
6. 6
   기타evaporated
7. 7
   기타to remove the solvent
8. 8
   workup.DISTILLATIONdistilled
9. 9
   기타giving

실험 절차

Methyl 6-bromodecanoate (1.2 g) and quinoline (1.2g) were mixed together, and then allowed to react at 240° C. for 5 minutes. After the reaction was completed, the reaction solution was extracted with ether, washed with dilute sulfuric acid, washed with water, dried, evaporated to remove the solvent, and then distilled, thereby giving a mixture of methyl 5-decenoate and methyl 6-decenoate (310 mg). The mixture was hydrolyzed in a coventional manner, thereby giving a mixture (270 mg) of 5-decenoic acid and 6-decenoic acid (1/1).

출처