반응 #93611

반응 방정식

5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid

triethanolamine

→

Tris-(2-hydroxyethyl)ammonium 5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoate

용매

glyme

glyme

반응 조건

후처리

1. 1
   workup.STIRRINGAfter stirring for a few hours the solvent
2. 2
   기타is removed in vacuo
3. 3
   기타the product is triturated repeatedly with petroleum ether (bp 30°-60° C.)
4. 4
   기타dried to a weight of 2.5 g

실험 절차

5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid (3.0 g, 0.0083 mole) is dissolved in glyme (20 ml) and a solution of triethanolamine (1.35 g, 0.0091 mole) in glyme (5 ml) is added rapidly while stirring at room temperature. After stirring for a few hours the solvent is removed in vacuo, the product is triturated repeatedly with petroleum ether (bp 30°-60° C.) and dried to a weight of 2.5 g. Anal. Calcd. for C20H22ClF3N2O8 : C, 47.02; H, 4.34; Cl, 6.39; N, 5.48; F, 11.15. Found: C, 47.08; H, 4.78; Cl, 6.48; N, 5.21; F, 10.16.

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