반응 #935898

ord-29a10da464654caca79df4dcc547a114

반응 방정식

C[C@@H]1O[C@@H](O[C@H]2[C@H](Oc3cc(O)c4c(c3)O[C@H](c3ccc(O)cc3)CC4=O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
naringin
C[C@@H]1O[C@@H](O[C@H]2[C@H](Oc3cc(O)c4c(c3)O[C@H](c3ccc(O)cc3)CC4=O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
naringin
→
O=C1C[C@@H](c2ccc(O)cc2)Oc2cc(O)cc(O)c21
naringenin

반응물

C[C@@H]1O[C@@H](O[C@H]2[C@H](Oc3cc(O)c4c(c3)O[C@H](c3ccc(O)cc3)CC4=O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
naringin
C[C@@H]1O[C@@H](O[C@H]2[C@H](Oc3cc(O)c4c(c3)O[C@H](c3ccc(O)cc3)CC4=O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
naringin

시약

없음

용매

Cl
hydrochloric acid

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    온도refluxing
  2. 2
    기타to form a yellow to red-brown solution
  3. 3
    기타As the reaction proceeds
  4. 4
    기타a yellow solid precipitates
  5. 5
    온도The solution is cooled
  6. 6
    여과the yellow solid filtered
  7. 7
    세척washed with copious amounts of water until the washings

실험 절차

616.5 grams naringin were added to a round bottomed flask, followed by the addition of about one liter of 0.5 N hydrochloric acid. Upon stirring and refluxing, the naringin dissolves to form a yellow to red-brown solution. While a brown gummy or oily material initially forms, it eventually disappears. As the reaction proceeds, a yellow solid precipitates. The reaction time is approximately 2 to 4 hours. The solution is cooled, and the yellow solid filtered and washed with copious amounts of water until the washings are no longer acidic. The amount of naringenin produced is about 160 grams.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04297348uspto-grants-1981_10