반응 #93525

반응 방정식

1-chloro-4-(4-chlorobutyl)benzene

1,2-dimethyl-1H-imidazole

→

title compound

1-[4-(4-Chlorophenyl)butyl]-2,3-dimethylimidazolium chloride

반응 조건

후처리

1. 1
   기타the progress of the reaction by thin-layer chromatography on silica gel (MeOH: NaCl(1M), 92:8)
2. 2
   기타At the completion of the reaction
3. 3
   온도cool
4. 4
   기타to obtain an oil
5. 5
   기타Triturate the oil with petroleum ether until a solid
6. 6
   기타precipitates
7. 7
   기타Recrystallize the solid from MeOH/ acetone
8. 8
   여과filter
9. 9
   기타dry in vacuo

실험 절차

To 4.77 g (0.023 mole) 1-chloro-4-(4-chlorobutyl)benzene add 2.23 g (0.023 mole) 1,2-dimethyl-1H-imidazole. Stir the solution for three hours at about 115° C. Follow the progress of the reaction by thin-layer chromatography on silica gel (MeOH: NaCl(1M), 92:8). At the completion of the reaction, cool to obtain an oil. Triturate the oil with petroleum ether until a solid precipitates. Recrystallize the solid from MeOH/ acetone; filter and dry in vacuo to yield the title compound as a monohydrate.

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