반응 #93293

반응 방정식

1-Methyl-4-pyridinone

1,3-dimethyl-5-pyrazolamine

→

4-(1,2,5,6-tetrahydro-1-methyl-4-pyridinyl)-1,3-dimethyl 5-(1H)-pyrazolamine

반응 조건

후처리

1. 1
   workup.DISTILLATIONAfter distillation under vacuum the residue
2. 2
   workup.ADDITIONis poured into water and neutralized with NaOH 10%
3. 3
   여과The compound of the title is recovered by filtration

실험 절차

1-Methyl-4-pyridinone (1.1 mole) is added to 1,3-dimethyl-5-pyrazolamine (1 mole). The reaction mixture is kept at a temperature between 70° C. and 80° C. for a period of about 8 hours. After distillation under vacuum the residue is poured into water and neutralized with NaOH 10%. The compound of the title is recovered by filtration. M.p. 262°-265° C.

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