반응 #93238

반응 방정식

Acetic anhydride

5-hydroxy-12H-benzo[a]phenothiazine

→

title compound

5-acetoxy-12H-benzo[a]phenothiazine

용매

pyridine

반응 조건

후처리

1. 1
   농축The reaction mixture was concentrated under vacuum and ice-water
2. 2
   workup.ADDITIONwas added to the residue
3. 3
   여과The resulting precipitate was filtered
4. 4
   기타air-dried
5. 5
   세척washed with ethyl acetate

실험 절차

Acetic anhydride (2 ml) was added to a solution of 5-hydroxy-12H-benzo[a]phenothiazine (1) (1.4 gm) in pyridine (10 ml) and stirred for 15 minutes. The reaction mixture was concentrated under vacuum and ice-water was added to the residue. The resulting precipitate was filtered, air-dried and washed with ethyl acetate to afford the title compound.

출처