반응 #93138

반응 방정식

2,6-dinitrobenzonitrile

piperidine

water

→

2-nitro-6-piperidinobenzonitrile

용매

dimethylformamide

반응 조건

후처리

1. 1
   온도while externally cooling because of heat generation
2. 2
   기타the precipitate thus formed
3. 3
   기타was collected
4. 4
   세척washed with water
5. 5
   건조with methanol, and dried

실험 절차

5.8 g of 2,6-dinitrobenzonitrile was dissolved in 30 ml of dimethylformamide, and 10.2 ml of piperidine was added to the solution. The mixture was stirred at 50° C. for 30 minutes while externally cooling because of heat generation. The reaction mixture was poured into water, and the precipitate thus formed was collected, washed with water and then with methanol, and dried to obtain 6.7 of 2-nitro-6-piperidinobenzonitrile (melting point: 122°-123° C.).

출처