반응 #92969

반응 방정식

water

2-methyl-4-chlorophenol

1,4-dichloro-2-butanol

sodium hydroxide

→

4-Chloro-1-(4-chloro-2-methylphenoxy)-2-butanol

용매

tertiary butanol

반응 조건

후처리

1. 1
   기타according to the procedure of Preparation 4 using 105 g
2. 2
   기타There was obtained 84 g
3. 3
   workup.DISTILLATION(45.5%) of product which distilled at 135° C./0.01 mm

실험 절차

4-Chloro-1-(4-chloro-2-methylphenoxy)-2-butanol was prepared according to the procedure of Preparation 4 using 105 g. (0.74 mole) of 2-methyl-4-chlorophenol, 171.5 g. (1.2 mole) of 1,4-dichloro-2-butanol, 50.3 g. of sodium hydroxide, 300 ml. of water and 300 ml. of tertiary butanol. There was obtained 84 g. (45.5%) of product which distilled at 135° C./0.01 mm.

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