반응 #92935

반응 방정식

1-(4-methylphenyl)-1-oxo-2-bromopropane

1-methylimidazole

→

1-methyl-3-[1-methyl-2-(4-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide

수율 11.0%

용매

diethyl ether

반응 조건

후처리

1. 1
   기타The reaction solvent was decanted
2. 2
   세척the residue was washed with diethyl ether
3. 3
   workup.DISSOLUTIONdissolved in acetonitrile
4. 4
   workup.ADDITIONThe resulting solution was diluted with diethyl ether
5. 5
   여과the precipitated solid was collected by filtration
6. 6
   기타The solid was recrystallized from acetonitrile/diethyl ether

실험 절차

A solution 2.24 g (0.01 mol) of 1-(4-methylphenyl)-1-oxo-2-bromopropane and 0.9 g (0.011 mol) of 1-methylimidazole in 50 ml of diethyl ether was stirred at room for approximately 18 hours. The reaction solvent was decanted, and the residue was washed with diethyl ether and dissolved in acetonitrile. The resulting solution was diluted with diethyl ether and the precipitated solid was collected by filtration. The solid was recrystallized from acetonitrile/diethyl ether to afford 0.33 g of 1-methyl-3-[1-methyl-2-(4-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide as a solid. (11% yield) mp=175°-177° C.

출처