반응 #92934

반응 방정식

1-phenyl-1-oxo-2-bromopropane

1-methylimidazole

→

1-methyl-3-(1-methyl-2-phenyl-2-oxoethyl)-1H-imidazolium bromide

수율 55.0%

용매

diethyl ether

반응 조건

후처리

1. 1
   여과The precipitated solid was collected by filtration
2. 2
   세척washed with diethyl ether
3. 3
   workup.DISSOLUTIONdissolved in methanol
4. 4
   workup.ADDITIONThis solution was diluted with diethyl ether
5. 5
   여과the resulting white solid was collected by filtration
6. 6
   기타This solid was recrystallized from methanol/diethyl ether

실험 절차

A solution of 8 ml (0.047 mol) of 90% pure 1-phenyl-1-oxo-2-bromopropane and 4.25 g (0.052 mol) of 1-methylimidazole in 100 ml of diethyl ether was stirred at room temperature for approximately 24 hours. The precipitated solid was collected by filtration, washed with diethyl ether and dissolved in methanol. This solution was diluted with diethyl ether and the resulting white solid was collected by filtration. This solid was recrystallized from methanol/diethyl ether to afford 7.65 g of 1-methyl-3-(1-methyl-2-phenyl-2-oxoethyl)-1H-imidazolium bromide as white crystals. (55% yield) mp=167°-170° C.

출처