반응 #92933

반응 방정식

1-bromo-2-(2-methylphenyl)-2-oxoethane

1-methylimidazole

→

1-methyl-3-[2-(2-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide

수율 34.0%

용매

diethyl ether

반응 조건

후처리

1. 1
   기타The reaction solvent was decanted
2. 2
   세척the residue was washed with diethyl ether
3. 3
   workup.DISSOLUTIONThe residue was dissolved in hot acetonitrile
4. 4
   온도the resulting solution was cooled
5. 5
   workup.ADDITIONdiluted with diethyl ether
6. 6
   기타The solid was collected
7. 7
   기타recrystallized twice from acetonitrile/diethyl ether

실험 절차

A solution of 4.22 g (0.02 mol) of 1-bromo-2-(2-methylphenyl)-2-oxoethane, 2.64 g (0.032 mol) of 1-methylimidazole and 60 ml of diethyl ether was stirred at room temperature for approximately 17 hours. The reaction solvent was decanted and the residue was washed with diethyl ether. The residue was dissolved in hot acetonitrile, and the resulting solution was cooled and diluted with diethyl ether. The solid was collected and recrystallized twice from acetonitrile/diethyl ether to afford 1.99 g of 1-methyl-3-[2-(2-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide as white needles. (34% yield) mp=152°-154° C.

출처