반응 #92932

반응 방정식

1-bromo-2-(4-ethylphenyl)-2-oxoethane

1-methylimidazole

→

1-methyl-3-[2-(4-ethylphenyl)-2-oxoethyl]-1H-imidazolium bromide

수율 38.2%

용매

diethyl ether

반응 조건

후처리

1. 1
   기타The reaction solvent was decanted
2. 2
   세척the residue was washed with diethyl ether
3. 3
   workup.DISSOLUTIONdissolved in a small amount of acetonitrile
4. 4
   workup.ADDITIONThe resulting solution was diluted with a small amount of ethyl acetate, whereupon a brown precipitate
5. 5
   기타formed
6. 6
   기타The solid was collected
7. 7
   기타recrystallized from acetonitrile/ethyl acetate

실험 절차

A solution of 4.41 g (0.019 mol) of 1-bromo-2-(4-ethylphenyl)-2-oxoethane and 1.65 g (0.02 mol) of 1-methylimidazole in 40 ml of diethyl ether was stirred at room temperature for approximately 18 hours. The reaction solvent was decanted, and the residue was washed with diethyl ether and dissolved in a small amount of acetonitrile. The resulting solution was diluted with a small amount of ethyl acetate, whereupon a brown precipitate formed. The solid was collected and recrystallized from acetonitrile/ethyl acetate to provide 2.26 g of 1-methyl-3-[2-(4-ethylphenyl)-2-oxoethyl]-1H-imidazolium bromide as fine yellow brown needles. (38% yield) mp=177°-179° C.

출처