반응 #9275

ord-a32947a36a4c48d3857c5a4f444f36ff

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    온도while cooling on ice
  2. 2
    기타to precipitate crystals, which
  3. 3
    여과were collected by filtration
  4. 4
    기타dried under reduced pressure

실험 절차

After dissolving 2-(1-butynyl)pyridine (12.8 g) in dichloromethane (60 mL), a solution of O-mesitylenesulfonylhydroxyamine (Reference document: Synthesis, 1997, 1) (20 g) in dichloromethane (132 mL) was added dropwise while cooling on ice, and the mixture was stirred for 30 minutes. Diethyl ether (2 L) was added to the reaction mixture to precipitate crystals, which were collected by filtration and dried under reduced pressure to obtain N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate (12.6 g) as colorless crystals.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07091215B2uspto-grants-2006_08