반응 #927241

반응 방정식

diethylether

2,3-dibromopropene

pentylmagnesium bromide

diethyl ether

hydrochloric acid

→

2-bromo-oct-1-ene

반응 조건

후처리

1. 1
   온도While cooling in an ice water bath
2. 2
   온도cooling in an ice water bath
3. 3
   기타The resulting mixture was transferred to a separatory funnel
4. 4
   기타the phases were separated
5. 5
   건조The organic layer was dried over MgSO4
6. 6
   여과filtered
7. 7
   기타The solvent was removed from the filtrate in vacuo

실험 절차

A solution of 9.42 ml (0.0728 mol) of 2,3-dibromopropene in 70 ml diethylether was placed under a nitrogen atmosphere by use of a Firestone valve. While cooling in an ice water bath, a solution of 0.091 mol of pentylmagnesium bromide in 70 ml diethyl ether was added slowly via addition funnel. After stirring for 2 hours while warming to room temperature, there was then added via syringe 50 ml of 1 N hydrochloric acid to the reaction cooling in an ice water bath. The resulting mixture was transferred to a separatory funnel and the phases were separated. The organic layer was dried over MgSO4 and filtered. The solvent was removed from the filtrate in vacuo to yield 15.0 g (85.7% of theory) of 81% pure 2-bromo-oct-1-ene as an oil.

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