반응 #927225

반응 방정식

water

triethylamine

para-acetylaminophenol

lauroyl chloride

→

Lauroyl [4-(N-acetylamino)]phenol

수율 12.0%

용매

DMF

반응 조건

후처리

1. 1
   기타the product precipitates
2. 2
   세척It is washed with heptane
3. 3
   기타dried under vacuum

실험 절차

An equivalent amount in moles of para-acetylaminophenol and lauroyl chloride are placed in contact at 0° C. in DMF (dilution=15%) in the presence of one molar equivalent of triethylamine. The mixture is allowed to warm to room temperature with stirring and the reaction medium is then poured into water and the product precipitates. It is washed with heptane and then dried under vacuum. The yield is 12%. The elemental analysis is in accordance with the structure.

출처