반응 #92676

반응 방정식

3-(cyclohexylmethoxy)-5-methyl-2-nitropyridine

→

3-(cyclohexylmethoxy)-5-methylpyridin-2-amine

수율 87.1%

용매

THF

반응 조건

후처리

1. 1
   여과The reaction mixture was filtered over Celite
2. 2
   기타the solvent was then evaporated under reduced pressure

실험 절차

To a solution of 1.8 g of 3-(cyclohexylmethoxy)-5-methyl-2-nitropyridine in 16 ml of THF was added 325 mg of 10% palladium-carbon (wet), followed by stirring for 3 hours under a hydrogen atmosphere. The reaction mixture was filtered over Celite and the solvent was then evaporated under reduced pressure to obtain 1.38 g of 3-(cyclohexylmethoxy)-5-methylpyridin-2-amine.

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