반응 #91814

반응 방정식

( i )

Ethyl 2-(oxetan-3-ylidene)propanoate

→

Ethyl 2-(oxetan-3-yl)propanoate

용매

EtOH

반응 조건

후처리

1. 1
   기타The reaction was degassed
2. 2
   기타purged with hydrogen at balloon pressure (×3)
3. 3
   여과The reaction mixture was filtered
4. 4
   세척the residue washed with acetonitrile (10 mL)
5. 5
   농축The combined organics were concentrated in vacuo
6. 6
   기타the residue, (ii) (148 mg), was used without further purification

실험 절차

To a solution of (i) (151 mg, 0.97 mmol) in EtOH (54 mL) was added 10% Pd/C (50 mg, 0.05 mmol). The reaction was degassed and purged with hydrogen at balloon pressure (×3) then stirred under hydrogen at RT for 16 h. The reaction mixture was filtered and the residue washed with acetonitrile (10 mL). The combined organics were concentrated in vacuo and the residue, (ii) (148 mg), was used without further purification.

출처