반응 #91323

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4-phenoxybenzylamine

3-fluoroisonicotinic acid

→

title compound

수율 36.0%

3-[(4-phenoxybenzyl)amino]pyridine-4-carboxylic acid

수율 36.0%

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실험 절차

The title compound was prepared in 36% yield from 4-phenoxybenzylamine and 3-fluoroisonicotinic acid according to the procedure for the preparation of Example 3. 1H NMR (400 MHz, DMSO-d6): δ 13.42 (br s, 1H), 8.18 (s, 1H), 7.83 (d, 1H, J=5.0 Hz), 7.57 (d, 1H, J=5.0 Hz), 7.35-7.40 (m, 4H), 7.13 (t, 1H, J=7.2), 6.97-7.02 (m, 4H), 4.55 (s, 2H). [M+H] calc'd for C19H16N2O3, 321. found 321.

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