반응 #91319

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4-phenylbenzylamine

3-fluoroisonicotinic acid

→

title compound

수율 36.0%

3-[(biphenyl-4-ylmethyl)amino]pyridine-4-carboxylic acid

수율 36.0%

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실험 절차

The title compound was prepared in 36% yield from 4-phenylbenzylamine and 3-fluoroisonicotinic acid according to the procedure for the preparation of Example 3. 1H NMR (400 MHz, DMSO-d6): δ 13.55 (br s, 1H), 8.17 (s, 1H), 7.83 (d, 1H, J=5.0 Hz), 7.71 (m, 4H), 7.58 (d, 1H, J=5.0 Hz), 7.32-7.48 (m, 5H), 4.62 (s, 2H). [M+H] calc'd for C19H16N2O2, 305. found 305.

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