반응 #91316

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4-methoxybenzylamine

3-fluoroisonicotinic acid

→

title compound

수율 26.0%

3-[(4-methoxybenzyl)amino]pyridine-4-carboxylic acid

수율 26.0%

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실험 절차

The title compound was prepared in 26% yield from 4-methoxybenzylamine and 3-fluoroisonicotinic acid according to the procedure for the preparation of Example 3. 1H NMR (400 MHz, DMSO-d6): δ 8.17 (s, 1H), 7.81 (d, 1H, J=5.0 Hz), 7.56 (d, 1H, J=5.0 Hz), 7.29 (d, 2H, J=8.5 Hz), 6.91 (d, 2H, J=8.5 Hz), 4.47 (s, 2H), 3.73 (s, 3H). [M+H] calc'd for C14H14N2O3, 259. found 259.

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