반응 #902

반응 방정식

2-methyl-3-nitro-6-acetamidobenzoic acid

HCl

→

2-Methyl-3-nitro-6-aminobenzoic acid

용매

NaOH

반응 조건

후처리

1. 1
   온도After cooling to 10° C.
2. 2
   여과the precipitate which deposits is filtered off with suction
3. 3
   세척washed with water
4. 4
   기타dried under reduced pressure at 50° C.

실험 절차

450 ml of 2N NaOH are initially taken and 75.6 g (0.317 mol) of 2-methyl-3-nitro-6-acetamidobenzoic acid are added. The reaction mixture is then warmed to 95° C. and is stirred at this temperature for one hour. After cooling to 10° C., it is acidified by addition of 425 ml of 2N HCl, and the precipitate which deposits is filtered off with suction, washed with water and dried under reduced pressure at 50° C.

출처