반응 #899

반응 방정식

m-(trifluoromethyl)phenol

NaH

4,6-dibromo-2-(methylthio)pyrimidine

→

phenoxide

4-bromo-2-methylthio-6-[3-(trifluoromethyl)phenoxy]pyrimidine

용매

THF

반응 조건

후처리

1. 1
   workup.ADDITIONVII-22) (2.0 g, 0.00794 mol) was added
2. 2
   기타to react for 5 hours at room temperature

실험 절차

In THF, a phenoxide was prepared from m-(trifluoromethyl)phenol (1.30 g, 0.00794×1.0 mol) and NaH (0.32 g (ca. 60% in mineral oil), 0.00794×1.0 mol), and 4,6-dibromo-2-(methylthio)pyrimidine (Compound No. VII-22) (2.0 g, 0.00794 mol) was added thereto, and the mixture was then allowed to react for 5 hours at room temperature.

출처