반응 #8986

ord-4a51539e54e6499c8098a02ac20b71d4

반응 방정식

[Na+].[OH-]
NaOH
c1c[nH]c(C2CC2)n1
2-cyclopropyl-1H-imidazole
Ic1nc(C2CC2)[nH]c1I
4,5-diiodo-2-cyclopropyl-1H-imidazole
O=S([O-])[O-].[Na+].[Na+]
sodium sulfite
II
iodine
Ic1cnc(C2CC2)[nH]1
title compound
Ic1cnc(C2CC2)[nH]1
2-Cyclopropyl-5-iodo-1H-imidazole

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The title compound was prepared in accordance with the literature reference of Cliff & Pyne, Synthesis-Stuttgart (7), 681–682(1994) by reacting 2-cyclopropyl-1H-imidazole with iodine in the presence of NaOH. The obtained 4,5-diiodo-2-cyclopropyl-1H-imidazole was then reacted with sodium sulfite to obtain the title compound.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07091222B2uspto-grants-2006_08