반응 #8980

ord-08a2d881db674a16b9f53b7e318f89a5

반응 방정식

Cc1cc(C#Cc2c[nH]c(C)n2)ccn1
2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine
CS(=O)(=O)OCC(F)(F)F
2,2,2-trifluoroethyl mesylate
Cc1cc(C#Cc2cn(CC(F)(F)F)c(C)n2)ccn1
title compound
Cc1cc(C#Cc2cn(CC(F)(F)F)c(C)n2)ccn1
2-Methyl-4-[2-methyl-1-(2,2,2-trifluoro-ethyl)-1H-imidazol-4-ylethynyl]-pyridine

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The title compound, MS: m/e=280.1 (M+H+), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 2,2,2-trifluoroethyl mesylate.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07091222B2uspto-grants-2006_08