반응 #89604

반응 방정식

3,4-Dimethyl-pentanal

Dibutylamine

acetic acid

formaldehyde

→

3,4-dimethyl-2-methylene-pentanal

용매

toluene

반응 조건

후처리

1. 1
   workup.WAITaged for another hour
2. 2
   온도The reaction mixture was cooled down
3. 3
   세척The reaction mixture was sequentially washed with water (2 L), sodium carbonate solution (1 L), and brine (1 L)

실험 절차

Dibutylamine (34 g), acetic acid (15.78 g), and formaldehyde (230 g) were charged to a reaction flask and heated to 70° C. 3,4-Dimethyl-pentanal (500 g) was fed over 2 hours and aged for another hour. The reaction mixture was cooled down and toluene (200 mL) was added. The reaction mixture was sequentially washed with water (2 L), sodium carbonate solution (1 L), and brine (1 L) to provide the crude product 3,4-dimethyl-2-methylene-pentanal.

출처