반응 #88129

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2-[5-(4-Nitro-phenyl)-pyrazol-1-yl]-pyridine

intermediate K

2-[5-(4-Nitro-phenyl)-pyrazol-1-yl]-pyridine

2-(4-fluoro-phenyl)-acetonitrile

→

title compound

3-(4-Fluoro-phenyl)-5-(2-pyridin-2-yl-2H-pyrazol-3-yl)-benzo[c]isoxazole

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실험 절차

The title compound, light green solid (65 mg, 49%), MS (ISP) m/z=357.1 [(M+H)+], mp 175° C., was prepared in accordance with the general method of example 1 from 2-[5-(4-Nitro-phenyl)-pyrazol-1-yl]-pyridine (intermediate K) (100 mg, 353 μmol) and commercially available 2-(4-fluoro-phenyl)-acetonitrile.

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