반응 #88119

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1-(4-chloro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole

intermediate H

1-(4-chloro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole

2-(4-fluoro-phenyl)-acetonitrile

→

title compound

5-[2-(4-Chloro-phenyl)-2H-pyrazol-3-yl]-3-(4-fluoro-phenyl)-benzo[c]isoxazole

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실험 절차

The title compound, yellow solid (28 mg, 22%), MS (ISP) m/z=390.2 [(M+H)+], mp 154° C., was prepared in accordance with the general method of example 1 from 1-(4-chloro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole (intermediate H) (100 mg, 353 μmol) and commercially available 2-(4-fluoro-phenyl)-acetonitrile.

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