반응 #88114

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1-(4-methoxy-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole

intermediate G

1-(4-methoxy-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole

2-(4-fluoro-phenyl)-acetonitrile

→

title compound

3-(4-Fluoro-phenyl)-5-[2-(4-methoxy-phenyl)-2H-pyrazol-3-yl]-benzo[c]isoxazole

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실험 절차

The title compound, light green solid (51 mg, 39%), MS (ISP) m/z=386.2 [(M+H)+], mp 179° C., was prepared in accordance with the general method of example 1 from 1-(4-methoxy-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole (intermediate G) (100 mg, 353 μmol) and commercially available 2-(4-fluoro-phenyl)-acetonitrile.

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